Determination of Antibiotics and Other Components in Medicinal-lotion and Evaluation

The aim of this paper is to know the compositions in unknown medicinal-lotion and to evolution its applications. Through a variety of studies, an analysis method was established. This method mainly is that samples were first extracted and pre-treated by concentration of compositions, and then they were separated and qualitatively analyzed by multiple-instruments. These instruments involve Mass Spectrum (MS), Fourier transform infrared (FT-IR) and High Performance Liquid Chromatography (HPLC). The qualitative analysis were done by using four different diagnostic indices using the single stage MS analysis identification; the characteristics of FT-IR; the measurements of the retention time in the HPLC and the choice characteristics of compositions in sample to HPLC detectors. The chloramphenicol was found to be the main antibiotic in the medicinal-lotion. The other compositions were roxithromycin, dexamethasone, ethylene glycol, 1, 2-propanediol and ethanol. The quantitative determination of these compounds was measurement by HPLC external standards method, and this medicinal-lotion was also evaluated.